CONTENTS


Introduction

Below, you will find some examples of screen sharing exercises that interviewers for a bioinformatics position at a company that does genetic research associated with food and human health might ask a candidate to perform.

It is important to note that the specific exercises that you are asked to perform during a screen sharing interview will vary depending on the company and the specific role that you are interviewing for. However, the examples above should give you a good idea of the types of tasks that you can expect to be asked to complete.


Examples

Project organization

In a collaborative project environment, how can you guarantee that the code will run on a collaborator's computer after you push new updates to GitHub?

BLAST

Using Python or R, read and sort results from a BLAST analyses to get only the best match for each entry based on E-value and bit-score.

Data Cleaning and Preprocessing

Given a raw dataset containing genetic information, perform quality control checks, filter out low-quality data, and perform any necessary preprocessing steps.

Genomic Variant Calling

Demonstrate how to call genetic variants (SNPs, indels) from raw sequencing data using a bioinformatics tool or pipeline (e.g., GATK, samtools).

Genome Assembly

If provided with raw sequencing reads, show how you would reconstruct the full genome.

Differential Gene Expression Analysis

Given RNA-seq data from different conditions, perform differential gene expression analysis using tools like DESeq2 or edgeR.